手性三元铜(Ⅱ)配合物的制备及其在菊酸不对称合成中的应用

CHIRAL TERNARY COPPER(Ⅱ) COMPLEXES: PREPARATION AND USE IN ASYMMETRIC SYNTHESIS OF CHRYSANTHEMIC ACID

手性金属配合物催化剂在不对称合成中占有重要地位。在该类催化剂参与的不对称催化反应中,配合物中手性配体是催化反应立体选择性优劣的关键。为了改进该类催化剂的性能,主要对手性配体进行过化学修饰。

Five chiral ternary complexes have been prepared from bidentate ligands contaning N-N coordinating sites and chiral oxy-acids with copper(Ⅱ). Their properties as chiral catalysts in the asymmetric synthesis of chrysanthemic acid have been examined.