复方吉祥草含片质量标准研究

Study on quality standard for Jixiangcao Buccal Tablets

目的 :提高复方吉祥草含片 (吉祥草、紫菀、鱼腥草、罂粟壳、麻黄等 )质量标准。方法 :采用薄层层析法对处方中的吉祥草、罂粟壳进行了定性鉴别 ;用高效液相法测定了含片中盐酸麻黄碱的含量。结果 :TLC鉴别方法专属性强 ;含量测定盐酸麻黄碱在 0 .4 0 4～ 2 .0 2 μg范围内 ,有良好线性关系 ,回收率为 97.0 3% ,RSD为 2 .2 % ;结论

AIM: To establish the quality standard for Jixiangcao Buccal Tablets(Herba Reineckea Camea, Radix Asteris, Heaba Houttugnlae, Pericarpium Papaveris, Heaba Ephedrae etc.). METHODS: TLC was used for the identification of Herba Reineckea Camea and Pericarpium Papaveris. HPLC was used for the determination of ephedrine hydrocholoride in the Buccal tablets. RESULTS: TLC identification was highly specific and the spots were clear. The linear range for ephedrine hydrocholoride was in the range of 0.404～2.02μg and its average recovery was 97.03% and RSD 2.2%, respectively. CONCLUSION: The quality standard is able to effectively control the quality of Jixiangcao Buccal Tablets.