脂肝乐胶囊治疗脂肪肝的临床研究

Study of fatty liver treated by Zhiganle capsule

目的 探讨中药脂肝乐胶囊治疗脂肪肝的临床疗效。方法 2 0 1例脂肪肝患者随机分为 2组 ,治疗组 1 0 1例用脂肝乐胶囊 ,每次 2 .0～4.0g,每日 3次口服 ;对照组 1 0 0例用凯西莱片 ,每次 2 0 0mg,每日 3次口服。 2组均 2个月为 1疗程。观察 2组疗效及治疗前后肝功能、症状及体征、B超、肝脏脂肪沉积、血脂、肝纤四项变化情况。结果 治疗组总有效率 ( 92 .0 7% )明显优于对照组 ( 81 .0 0 % ,P <0 .0 5 ) ;治疗后治疗组在改善肝功能 ,改善B超肝脏脂肪沉积情况 ,降低甘油三酯、透明质酸 ,改善症状和体征方面与对照组比较有显著性差异(P <0 .0 5 或P <0 .0 1 ) ,治疗组在病理方面、改善肝脏脂肪沉积方面有确切疗效。结论 脂肝乐胶囊治疗脂肪肝疗效可靠。

Objective To study fatty liver treated by Zhiganle capsule. Methods 201 cases with fatty liver were randomly divided into two groups. Patients in treatment group (n=101) were given Zhiganle capsule, patients in control group (n=100) were given Tiopronin. Results The total effective rate in treatment group (92.07%) was markedly higher than that in control group (81.00%, P<0.05). Improvement of liver function, fat deposition, triglycerides and hyaluronate in treatment group were superior to those in control group (P<0.05 or P<0.01). Conclusion Zhiganle capsule could effectively treat fatty liver.