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哮喘的遗传易感性与染色体5q31-33的关系 被引量：4

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摘要 哮喘是一种以慢性非特异性炎症浸润、支气管高反应性为特征的、多基因参与的遗传性疾病 ,与染色体 5 q31 33区域的多个结构基因、调控基因及其表达产物有错综复杂的关系。本文对该区域的细胞因子基因簇、肾上腺素受体基因及其它相关基因与哮喘的遗传易感性的关系进行了系统地综述。提示 :哮喘的分子遗传学研究有助于在分子水平上了解其发病机制 ,为哮喘的诊断、治疗和预防提供新的策略和方法。
作者 张学智 韩爱萍 顾明亮
机构地区 胜利石油管理局中心医院检验科 胜利石油管理局中心医院儿科 胜利石油管理局中心医院医学中心实验室
出处 《国外医学（呼吸系统分册）》 2004年第1期4-6,共3页 Section of Respiratory System Foreign Medical Sciences
关键词 哮喘 遗传易感性 染色体 5q31-33
分类号 R562.25 [医药卫生—呼吸系统]
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参考文献14

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同被引文献61

  • 1张建华,丁云芳,陶慧,严永东,盛锦云.哮喘患儿ACE基因多态性和家族聚集性的研究[J].中华儿科杂志,2004,42(6):455-456. 被引量：4
  • 2中华医学会儿科分会呼吸学组.儿童支气管哮喘防治常规[R].北京,2003..
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  • 8Centers for Disease Control and Prevention ( CDC ).Reducing Childhood Asthma Through Community-Based Service Delivery-New York City,2001-2004[ J ].Weekly January 14,2005/54( 01 ),11-14.
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国外医学（呼吸系统分册）
2004年 第1期

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