北京市结肠癌危险因素的病例对照研究

A Case-Control Study for Colon Cancer in Beijing,China

筛选北京市结肠癌主要危险因素。方法:用1:1配对病例对照研究方法,调查150例原发性结肠癌患者,并用条件Logistic回归模型对所获资料进行单因素和多因素分析。结果:有统计意义的危险因素包括:食用油和高蛋白食品摄入过多、精神压抑等;保护因素有经常食用新鲜蔬菜和葱、醋等食品;而一些文献报道有统计意义的危险因素(如肠道慢性疾患史、家族肿瘤史等)本文未见统计意义。结论:该研究为了解北京市结肠癌的流行规律提供了参考。

Objective:A population-based case-control study was carried out to identify the risk factors for colon cancer in Beijing.Methods:150cases matched1:1with controls were interviewed.Conditional logistic regression was used in data analysis.Results:Some risk factors were found such as high consumption of cooking oil and protein,psychological repression.Decreased risks were observed for high consumption of fresh vegetable,shallot and vinegar.No statistically significant relationship existed between history of colon disease,smoking and colon cancer.Conclusion:The results were useful for the prevention and control of colon cancer in Beijing.