经尿道激光治疗前列腺增生症的远期疗效观察

Long-term effects of transurethral laser ablation of prostate for benign prostatic hyperplasia

目的 评价经尿道激光治疗前列腺增生症的远期疗效。 方法 回顾分析 1993年 11月～ 1999年 9月经尿道激光治疗前列腺增生症 72例 ,随访 3年～ 9年 ,平均 7 0年。 结果 手术前后国际前列腺症状评分 (IPSS)分别为 (2 7 5±2 6 )分和 (2 0 7± 4 2 )分 (t=11 6 8,P <0 0 0 1) ,生活质量指数 (QOL)分别为 (4 5± 0 6 )分和 (3 9± 0 8)分 (t=5 0 1,P <0 0 0 1) ,最大尿流率 (MFR)分别为 (6 9± 2 7)ml s和 (11 8± 4 1)ml s(t=- 8 5 2 ,P <0 0 0 1) ,前列腺体积分别为 (5 2 4± 5 2 )克和 (5 1 2± 6 7)克 (t=1 2 0 ,P >0 0 5 ) ,残余尿量 (PVR)分别为 (71 5± 4 6 2 )ml和 (4 2 3± 2 8 6 )ml(t=4 5 6 ,P <0 0 0 1)。 39例 (5 4 2 % )病人主观疗效评价满意。 结论 经尿道激光治疗前列腺增生症的远期治疗效果满意。

Objective To evaluate the long-term effectiveness of transurethral laser ablation of prostate in patients with benign prostatic hyperplasia (BPH). Methods We retrospectively reviewed 72 patients with BPH treated by transurethral laser ablation from November 1993 to September 1999. Follow-up observations ranged (3～9) years, mean 7 0 year. Results Pre- and post-operative International Prostate Symptom Score (IPSS), Quality of Life score (QoL), MFR, estimating weight of prostate and Post-Void Residual Urine (PVR) were (27 5±2 6) and (20 7±4 2) ( t =11 68, P <0 001), (4 5±0 6) and (3 9±0 8) ( t =5 01, P <0 001), (6 9±2 7) ml/s and (11 8±4 1) ml/s ( t =-8 52, P <0 001), (52 4±5 2) g and (51 2±6 7) g( t =1 20, P >0 05), (71 5±46 2) ml and (42 3±28 6) ml ( t =4 56, P <0 001), respectively. On questionnaire, 39 patients (54 2%) were satisfied. Conclusions Long-term effect of transurethral laser ablation of prostate for BPH is satisfactory.