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黄斑色素与黄斑区视锥细胞功能相互关系的临床观察 被引量:4

The clinical observation of the relationship between the macular pigment and the foveal cone function
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摘要 目的 探讨黄斑色素 (macular pigment,MP)与黄斑区视锥细胞功能的相互关系。 方法 对临床确诊的 16例 Stargardt患者的 32只眼 ,3例黄斑裂孔患者的 3只眼用激光扫描检眼镜 (scanninglaserophthalmoscope,SL O)进行黄斑区 MP密度的检测。通过 SL O的氩激光蓝色及红外波段进行 MP的诊断与密度分级。用自编的计算机 C+ + 程序进行 MP密度评估 ,并将 MP分为完整 MP、部分 MP及 MP缺失 3级。对比分析 MP分级与 Snellen视力检查结果的相互关系。 结果 视力低于 2 0 / 2 0 0的 13只眼全部表现为 MP缺失 ;视力等于或高于 2 0 / 4 0的 11只中 10只眼表现为完整 MP,1只眼表现为部分 MP;视力介于两者之间的 11只眼表现为部分 MP。检测结果无病种间的差别。 结论  MP与患者的视力密切相关 ,是黄斑区视锥细胞功能完整的标志。 Objective To test the hypothesis that the macular pigment may be a marker of foveal cone function and consequently the structural integrity of foveal cones. Methods Sixteen patients (32 eyes) diagnosed to have Stargardt dystrophy and three patients with full thickness macular holes by clinical criteria were studied with a scanning laser ophthalmoscopy (SLO) comparing argon laser blue and infra-red images for the presence or absence of macular pigment (MP) in the fovea. An C ++ computer based program was used to evaluate the density of MP. Eyes were graded into three categories: those without foveal macular pigment, those with partial pigment and those with normal amounts of macular pigment. These categories were compared with visual acuity determined by the Snellen chart. Results Thirteen eyes with a visual acuity of 20/200 or worse had no macular pigment in the fovea. Eleven eyes with visual acuity of 20/40 or better had a normal amount of macular pigment in the fovea and 1 eye had partial macular pigment. Eleven eyes with partial macular pigment had intermediary acuity value. Conclusions Foveal macular pigment is closely related to foveal cone acuity and therefore may be a marker for the presence of foveal cones. Infrared light is a sensitive indicator of early macular diseases
出处 《中华眼底病杂志》 CAS CSCD 2003年第4期213-216,共4页 Chinese Journal of Ocular Fundus Diseases
关键词 黄斑色素 黄斑区 视锥细胞功能 MP 视网膜穿孔 STARGARDT病 Macular lutea/physiopathology Retinal perforations/diagnosis Stargardt disease Microscopy,confocal Pigment epitheliu of Eye Software
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  • 1甘晓玲.弱视的定义、分类及疗效评价标准[J].中国斜视与小儿眼科杂志,1996,4(3):97-97. 被引量:1013
  • 2蒋爱民,降丽娟.儿童眼球震颤86例临床分析[J].中国斜视与小儿眼科杂志,1996,4(4):169-170. 被引量:1
  • 3吴芳,杨亚波.颜色视功能检查及其进展[J].国外医学(眼科学分册),2005,29(6):370-373. 被引量:9
  • 4王智勇,袁秀妹,马丹辉,李宏斌,李秀昌,贾维化,孙作庆.不同色度纸张对荧光灯和白炽灯反射的光谱对比[J].中国学校卫生,2006,27(8):660-661. 被引量:10
  • 5PHILIP H, STEFANIE K, TANJA W, et al. The retinal clock drives the expression of Kcnv2, a channel essential for visual function and cone survival [J]. Investigative Ophthalmology & Visual Science, 2012, 53 (11): 6947-6954.
  • 6BOWMAKER J. Evolution of vertebrate visual pigments [J]. Vision Research, 2008, 48 (2): 2022-2041.
  • 7ANDREW Stockman, LINDSAY T Sharpe. The spectral sensitivities of the middle- and long-wavelength-sensitive cones derived from measurements in observers of known genotype [ J ]. Vision Research, 2000, 40 (13): 1711-1737.
  • 8IGNAT I, OLEG M. Electromagnetic Conception for the Eyesight in Additive Mixing of Colors [ J ]. Journal of Health Medicine and Nursing, 2015, 09:15-33.
  • 9KAYLOR J J, COOK J D, JACOB M, et al. Identification of the 11-cis-specific retinyl-ester synthase in retinal MUller cells as muhifunctional O-acyltrans- ferase (MFAT) [ J]. Proceedings of the National Academy of Sciences, 2014, 111 (20) : 7302-7307.
  • 10DAVIES W I L, WILKIE S E, COWING J A, et al. Anion sensitivity and spectral tuning of middle- and long- wavelength-sensitive (MWS/LWS) visual pigments [ J ]. Cellular & Molecular Life Sciences Cmls, 2012, 69 (14) : 2455- 2464.

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