乙酰苯胺衍生物的~1H和^(13)C NMR谱的研究

Study on the ~1H, ^(13)C NMR OF Derivatives of Acetanilides

本文测定了10个乙酰苯胺衍生物的~1H,^(13)C NMR谱,采用质子自旋去偶,质子选择去偶,质子偏共振去偶,质子去偶的^(13)C DEPT和选择INEPT等技术对其谱线进行归属。系统地研究了围绕羰基碳氮键的受阻旋转,确认了该类化合物在溶液中存在E和Z型构象体,并探讨了各种取代基对形成异构体比例的影响。

in this paper ~1H and ^(13)C NMR spectra of 10 derivatives of acetanilides are recorded.The assignments of ~1H and ^(13)C NMR spectra of these compounds were confirmed by spindecoupled. selective proton decoupled. proton off-resonance decoupled, DEPT and selectiveINEPT techniques. The restricted rotation about the carbon-nitrogen bonds of the amide groupof acetanilides has been investigated. It has been proposed that the molecular structure of ace-tanilides in solution can be described in terms of an equilibrium between E-and Z-form. Theeffect of various substituents on conformation is discussed.