二氯亚甲基环己烷的卤化反应和2-取代二氯亚甲基环己烷的构象

The Helogenation Reactions of Dichloromethylenecyclohexane and Conformational Analysis of 2-Substituted Dichloromethylenecyclohexane

多卤代烃在有机反应机理和结构研究中有着重要意义,作为一个有用的合成中间体,其制备也受到人们重视。我们在此报道二氯亚甲基环已烷(1)与氯及溴的反应和其它有关反应的实验结果。 1 于氯作用,主要得到加成产物1—氯—1—

Besides addition product 2-halo-substiituted dichloromethylenecyclohexane by-produ- cts were produced from the reactions of the titled compound with chlorine and bromine. To prepare the compound 1-trichloromethylcyclohexene by a series of elimination reactions was unsuccessful. The axial conformer of 2-substituted dichloromethylenecyclohexane has been observed, which was interpreted in terms of anomeric effect.