摘要
探讨肉芽组织增生与再生的机理。对给外用制剂不同时期 ( 3d ,7d ,11d)皮肤溃疡的肉芽组织取样 ,通过免疫组化法检测VEGF、PCNA和ED1 的表达的变化了解到 :随着给药时间的延长 ,肉芽组织增生明显 ,VEGF、PCNA和ED1 表达增多 (P <0 0 1)。结果提示 ,VEGF、PCNA和M表达增强 。
To determine the function of hyperplasia and repopulation of granulation. The samples of skin ulcer’s granulation at different period (3 day, 7day, 11day) were observed for the change of expression of VEGF、PCNA and ED 1 by method of immunohistochemistry. The obviously increasing granulation was expressed by promoting VEGF、PCNA and ED 1 (P<0.01). It is concluded that expression growth factors such as VEGF、PCNA and M can promote the growing of granulation.
出处
《基础医学与临床》
CSCD
北大核心
2004年第1期34-36,共3页
Basic and Clinical Medicine
基金
黑龙江省自然基金 (D990 5 )
