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NF-κB与危重病治疗 被引量:1

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摘要 核因子 κB (NF κB)为一种参与多种炎症介质基因表达的转录因子。NF κB过度及长时间激活与许多炎性疾病 ,包括脓毒性休克、急性呼吸窘迫综合征 (ARDS)、缺血及再灌注损伤等有关。为减轻组织和器官损伤 ,NF κB在调控炎症中的重要作用使之成为一个治疗目标。通过基因治疗策略或药物抑制导致NF κB活化中的关键步骤 ,能调控NF κB信号转导。
出处 《国外医学(生理病理科学与临床分册)》 2004年第1期95-97,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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