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Synthesis of Metal Porphyrins Tailed with Salicylic Acid and their Interaction with Bovine Serum Albumin 被引量:2

Synthesis of Metal Porphyrins Tailed with Salicylic Acid and their Interaction with Bovine Serum Albumin
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摘要 A synthetic method of porphyrins tailed with salicylic substituents is described. Reaction of bromoalkoxyphenyl porphyrin 1 with salicylic acid gave porphyrins 2~5. These new compounds were confirmed by 1H NMR, IR, UV-vis, MS and elemental analysis, and observed their interaction with bovine serum albumin (BSA) in fluorescence spectrum. A synthetic method of porphyrins tailed with salicylic substituents is described. Reaction of bromoalkoxyphenyl porphyrin 1 with salicylic acid gave porphyrins 2~5. These new compounds were confirmed by 1H NMR, IR, UV-vis, MS and elemental analysis, and observed their interaction with bovine serum albumin (BSA) in fluorescence spectrum.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第3期357-360,共4页 中国化学快报(英文版)
关键词 METALLOPORPHYRINS salicylic acid synthesis bovine serum albumin fluorescence. Metalloporphyrins, salicylic acid, synthesis, bovine serum albumin, fluorescence.
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  • 1[1]J. Moan, K. Berg, Photochem.photobio, 1992, 55, 931.
  • 2[2]C. J. Gomer, Semin.Hematol, 1989, 26, 27.
  • 3[3]F. Carol, Lancet, 1997, 350, 418.
  • 4[4]F. Kees, D. Jehnich, H. Grobecker, Journal of Chromatography B, 1996, 677, 172.
  • 5[5]c (BSA) = 1.0×10-5mol/L, λex=290 nm, c (4 ) or (5) /105mol/L, 1 to 7= 0, 0.2, 0.4, 0.6, 0.8, 1.0, 1.5 × 10-5 mol/L of 4 or 5, respectively.

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