摘要
以竞争性RT PCR研究骨质疏松模型大鼠骨髓白细胞介素 6受体亚单位gp80和 gp13 0基因的表达。结果表明这些骨质疏松大鼠的 gp80和gp13 0mRNA基因表达增加 ,该变化可能为雌激素丢失所致骨质疏松的形成机制之一。
Gene expressions of interleukin-6 receptor subunit gp130 and gp80 were investigated by competitive RT-PCR in the rat model of osteoporosis. A significant increase in expressions of gp130 and gp80 was found in bone marrow of osteoporotic rat, this change may be a possible mechanism in osteoporosis due to loss of estrogen.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2003年第6期494-495,共2页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金资助 (30 0 70 357)