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骨质疏松大鼠骨髓白细胞介素6受体亚单位gp80和gp130基因的表达 被引量:1

Expressions of IL-6 receptor subunit gp80 and gp130 genes in bone marrow of osteoporotic rat
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摘要 以竞争性RT PCR研究骨质疏松模型大鼠骨髓白细胞介素 6受体亚单位gp80和 gp13 0基因的表达。结果表明这些骨质疏松大鼠的 gp80和gp13 0mRNA基因表达增加 ,该变化可能为雌激素丢失所致骨质疏松的形成机制之一。 Gene expressions of interleukin-6 receptor subunit gp130 and gp80 were investigated by competitive RT-PCR in the rat model of osteoporosis. A significant increase in expressions of gp130 and gp80 was found in bone marrow of osteoporotic rat, this change may be a possible mechanism in osteoporosis due to loss of estrogen.
作者 罗江 张秀珍
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2003年第6期494-495,共2页 Chinese Journal of Endocrinology and Metabolism
基金 国家自然科学基金资助 (30 0 70 357)
关键词 骨质疏松 大鼠 骨髓 白细胞介素6受体 亚单位 gp80 GP130 基因表达 雌激素丢失 Osteoporosis Receptors, interleukin-6 Rats, Sprague-Dawley
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同被引文献14

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