同种异体骨和自体骨髓移植治疗骨不连

Allogenous bone and autogenous bone marrow grafting for the treatment of bone nonunion

目的 :探讨用同种异体骨和自体骨髓移植治疗骨折不愈合的疗效。方法 :自 1997年 6月至 2 0 0 3年 6月 ,采用同种异体骨和自体骨髓移植治疗骨不连患者 2 6例。采用抽取自身红骨髓混合同种异体骨植入骨折处 ,并选用合适的固定材料固定。结果 :2 6例全部获得随访 ,时间为 6个月～ 2 6个月 ,平均 16个月。最终获骨折愈合。X线显示 :骨折线消失 ,有连续骨痂形成。结论 :自体骨髓移植在骨不连部位有良好的成骨作用 ,配合同种异体骨植入治疗和预防骨不连效果确切 ,疗效满意 ,有临床应用价值。

Objective :To investigate the effect of allogenous bone and autogenous bone marrow grafting on the treatment of bone nonunion.Method:From June 1997 to June 2003, 26 cases with bone nonunion were treated by allogenous bone and autogenous bone marrow grafting ,appropriate fixation material were applied in operation. Result :All 26 cases were followed up for 6 months to 26 months, the average follow up duration 16 months, all 26 cases of bone nonunion were healed, X-ray displaying fractional line disappeared and continuous callus formed.Conclusion:Allogenous bone and autogenous bone marrow grafting play a main role in osteogenesis at the site of nonunion, the effect is satisfactory, it has clinical application value.