摘要
目的 :研究狐狸皮下脂肪精制油的理化性质及脂肪酸含量。方法 :采用中国药典测定法及气相色谱法。结果 :狐狸油的相对密度 (2 0℃ / 2 0℃ )为 0 .9190 ,折光率 (2 0℃ )为 1.4 6 71~ 1.4 6 75 ,熔点为 2 7~ 37℃ ,5 2~ 5 7℃ ;酸值为 0 .88,皂化值为2 2 2 .16 ,碘值为 15 .4 7;脂肪酸分别为棕榈酸 18.6 2 %、棕榈油酸 6 .0 6 %、十八碳酸 8.77%、油酸 5 4 .36 %、亚油酸 7.80 %。结论 :狐狸油熔点适中 ,游离脂肪酸少 ,不饱和度低 ,对氧稳定 ,含多种脂肪酸 ,适合于外用制剂的开发。
OBJECTIVE To investigate the physical and chemical properties of fatty acid of fox oil. METHODS The standard methods for analyzing fat and fatty oil from the Pharmacopoeia of the People's Republic of China were used. The fatty acid was determined by gas chromatography. RESULTS The relativity density(20℃/20℃),index of refraction(20℃), the melting point were 0.9190 , 1.4671 ~ 1.4675 and 27~37℃,52~57℃,respectively;the acid value, iodine value, saponifying value were 0.88 , 222.16 and 15.47 ,respectively.Five fatty acids were determined as palmitic acid 18.62% ,palmitoleic acid 6.06%,stearic acid 8.77% ,oleic acid 54.36% and linoleic acid 7.80% . CONCLUSION The fox oil is suitable for the development of topical use preparation due to it's well situated melting point, little content of free fatty acid, lower unsaturated degree, stable to oxygen, and similar constituent of fatty acid in human skin.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2004年第3期144-145,共2页
Chinese Journal of Hospital Pharmacy
关键词
狐狸油
脂肪酸
理化性质
fox oil
fatty acid
physical and chenical properties