摘要
脱氢表雄酮(dehydroepiandrosterone,DHEA)是人体内多种激素合成的前体,有研究表明,DHEA开辟了通过调节免疫系统抗致死性感染的途径,其代谢产物雄烯二醇(androstenediol,AED)和雄烯三醇(androstenetriol,AET)具有更强的抗病毒和细菌感染的能力,降低机体的发病率和死亡率。
Dehydroepiandrosterone(DHEA)was considered to be a biologically irrelevant interme-diate in the pathway of steroid hormones.DHEA provides one of the first avenues by which the im-mune system can be globally regulated to increase resistance to a variety of lethal infections.The downstream metabolites of DHEA particularly androstenediol(AED)and androstenetriol(AET)were sig-nificantly more efficacious at preventing morbidity and mortality associated with viral and bacterial in-fection.
出处
《国外医学(放射医学核医学分册)》
2004年第1期44-46,共3页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)