生物能量在生命体中传递的新理论及应用

New Theory of Bio-energy Transport and Its Application in the Life System

生物能量在生物体当中的传递是生命科学中的一个基本问题 ,它相关于ATP水解放出的能量沿着蛋白质分子的传递。这种传递与蛋白质的动力学相关。根据ATP分子分布和水解的特性以及蛋白质结构的特点 ,在Davydov理论的基础上提出了一个新的生物能量传递的理论。在这个理论当中 ,Amide振动的集体激发状态用一个两量子准相干态表示 ,系统的哈密顿量不但包含了Amide振动引起的相邻氨基酸残基的位移 ,而且包含了相邻Amide之间的共振相互作用所引起的氨基酸残基的相对位置的改变。由这个理论得出的传递生物能量的孤子的寿命可得 10 - 10 秒 ,在这个时间之内孤子能传递过上千个氨基酸残基 ,因此它能在生物过程中起着重要的作用。这个理论与E .col.的Ramma谱的实验结果和我们做出的胶原蛋白的红外吸收谱等实验结果相一致 ,因此它可能是生物体中生物能量传递的一个可利用的和正确的理论。

Bioenergy transport in the living systems is a basic problem for the life science. It is related to transport of the energy released in APT hydrolysis along the protein molecules, and is determined by dynamic properties of the protein molecules. According to the distribution of ATP molecules and its features of hydrolysis and structure properties of protein molecules we proposed a new theory of bioenergy transport in protein molecules based on Davydov model. In this new model we represented the collective excitation of vibrational quanta of amide-I by a two-quantum quasi-coherent wave function, both displacement of amino acid residues arising from the vibration of amide-Is and relative displacement of neighboring amino acids caused by resonant interaction between neighboring amides were taken into account in the new Hamiltonian. The lifetime of the new soliton transported the bioenergy obtained from this theory is about 10 -10 second, in this time the soliton can move over more than one thousand of amino acid residues. This shows that the soliton is possibly a carrier of the bioenergy transport, and can play an important role in biological processes. The results obtained by this theory coincide with experimental data of E.Col.'s Ramma scattering and infrared absorption of collagen by us and others. Therefore, this theory is available and valuable in biology.