阿卡波糖在强化血糖控制中的作用分析

Acarbose and strengthening control plasma glucose

目的探讨阿卡波糖 (拜糖苹 )在强化血糖治疗中的作用。方法将 5 0例 2型糖尿病患者随机分为甲、乙两组 ,甲组单用格列吡嗪 (灭特尼 )治疗 ,乙组用格列吡嗪加阿卡波糖联合治疗 ,治疗前后进行空腹血糖 (FPG)、餐后 2小时血糖 (2HPG)及糖化血红蛋白 (HbA1c)比较。结果甲、乙两组经治疗后FPG、2HPG、HbA1c较治疗前均有下降 ,但两组之间在 2HPG、HbA1c降低程度上差异有显著性。结论阿卡波糖能有效降低餐后血糖 ,同时降低空腹血糖 ,使糖化血红蛋白显著下降 ,血糖得到良好控制 ,真正达到强化血糖控制的目的。

Objective To explore the effect of Acarbose on the strengthening control plasma glucose.Methods 50 cases were randomly divided into two groups,A group received the treatment of Glipizide,B group received the treatment of Glipizide and Acarbose.After treatment,comparing the changes of fasting plasma glucose,2h postprandial plasma glucose levels and HbA 1c.Results After treatment,fasting plasma glucose,2h postprandial plasma glucose levels and HbA 1c in two groups were reduced.the differences in reductions of 2h postprandial plasma glucose levels and HbA 1c between the two groups were statistically significant.Conclusion Acarbose can decrease both postprandial plasma glucose and fasting plasma glucose.It can provides an effective control of plasma glucose level.