生长抑素治疗轻型急性胰腺炎的疗效研究

The study on the effect that somatostatin treats mild acute pancreatitis

目的 研究生长抑素治疗轻型急性胰腺炎的疗效。方法 连续入院的轻型急性胰腺炎病人 14 0例 ,采用摸围棋子的方法将病人随机分为两组 :(1)实验组 ,善得定 0 .1mg皮下注射q8h ,连用 5天 ;甲腈咪呱 0 .8g静脉滴注qd ,连用 5天 ;丁胺卡那霉素 0 .6g静脉滴注qd ,连用 5天 ;禁食、胃肠减压、补液。 (2 )对照组 ,不使用善得定 ,其它治疗方法与实验组相同。结果 所有病例全部治愈 ,没有并发症发生。实验组腹痛持续时间及住院时间分别是 (3 9.72± 2 .0 1)小时及 (8.0 9± 0 .3 0 )天 ,对照组腹痛持续时间及住院时间分别是 (42 .96± 2 .2 2 )小时及 (8.48±0 .3 9)天 ,两组无显著性差异。

ObjectiveTo study on the effect that somat ostatin treats mild acute pancreatitis.Methods140 patien ts of mild acute pancreatitis were randomly assigned to two groups by taking th e chessman of I-go:(1)Experiment group(71 cases) respectively received 0.1mg of Sandostatin by subcutaneous injection three times daily, 0.8g of Cimetidine by infusion one time daily and 0.6g of amikacin by infusion one time daily for f ive days,and received fast, gastrointestinal decompression and fluid replacement .(2)Control group(69 cases) respectively received the same treatment as the expe riment group except Sandostatin.ResultsAll patients heal ed without one compication. The duration of abdominal pain and the length of t he hospital stay were respectively 39.72±2.01 hours and 8.09±0.30 days in the experiment group,and were respectively 42.96±2.22 hours and 8.48±0.39 days in the control group.There were no significant differences between the two grou ps. Conclusion The effect with Sandostatin treating mild acute pancreatitis is not transparent.