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A numerical simulation of photothermal response in laser medicine 被引量:3

A numerical simulation of pbotothermal response in laser medicine
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摘要 In this paper, we reported a numerical solution of laser induced thermal effect in the bio-tissue. The model of photothermal effect and classical Pennes bio-heat transfer equation were introduced. Finite element method (FEM), which was realized by Matlab software, was used to calculate the temperature distribution. He-Ne laser (633 nm) was used to simulate the physical therapy in in vivo skin tissue. Under the cylinder coordinates, the three-dimension(3-D) geometry of tissue was reduced to two-dimension(2-D) computation. The results contained the radial, axial and temperature 3-D color plot. Combining the time animation display was possible. By changing the laser and tissue parameters we can get different results. This will be the initial and indispensable work of the non-destructive evaluation of the laser induced injury. In this paper, we reported a numerical solution of laser induced thermal effect in the bio-tissue. The model of photothermal effect and classical Pennes bio-heat transfer equation were introduced. Finite element method (FEM), which was realized by Matlab software, was used to calculate the temperature distribution. He-Ne laser (633 nm) was used to simulate the physical therapy in in vivo skin tissue. Under the cylinder coordinates, the three-dimension(3-D) geometry of tissue was reduced to two-dimension(2-D) computation. The results contained the radial, axial and temperature 3-D color plot. Combining the time animation display was possible. By changing the laser and tissue parameters we can get different results. This will be the initial and indispensable work of the non-destructive evaluation of the laser induced injury.
出处 《Chinese Optics Letters》 SCIE EI CAS CSCD 2004年第3期157-159,共3页 中国光学快报(英文版)
基金 This work was supported by Tianjin Natural Science Foundation under Grant No. 023602611.
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  • 1马宁,李和杰,张学学.蒙特卡罗模拟激光诱导间质热疗中激光能量在肿瘤组织内的传播[J].工程热物理学报,2002,23(S1):101-104. 被引量:1
  • 2李小霞,范世福,赵友全,肖松山.光动力学疗法中光热效应的有限元法[J].光电子.激光,2004,15(7):881-884. 被引量:8
  • 3李小霞,范世福,赵友全,顾瑛,刘凡光,曾晶.Nd∶YAG激光照射大鼠皮肤组织的温度实验[J].中国激光医学杂志,2005,14(6):350-353. 被引量:3
  • 4WELCH A J, GEMERT J C. Optical-thermal Response of Laserirradiated Tissue [ M]. New York: Plenum Press, 1995, 367- 534.
  • 5杨洪钦,林清源,叶真,陈树强,谢树森.正常乳腺温度分布的有限元分析[J].激光生物学报,2007,16(4):424-427. 被引量:3
  • 6Loze, M. K. and Wright, C. D. Temperature Distributions in Laser- heated Semi- infinite and Finite- thickness Media with Convective Surface Losses [ J ]. Applied Optics, 1998, 37 (28) :6822 - 6832
  • 7Dan Zhu, Qingming Luo, Guangming Zhu, et al. Kinetic Thermal Response and Damage in Laser Coagulation of Tissue[J]. Lasers in Surgery and Medicine, 2002, 31:313 -321
  • 8Diaz, S. H., Aguihtr, G., Lavernia, E. J., et al. Modeling the Thermal Response of Porcine Cartilage to Laser Irradiation[J].IEEE Journal on Selected Topics in Quantum Electronics, 2001,7(6): 944 -951
  • 9Puccini, S. , Bar, N. K. and Bublat, M. Simulations of Thermal Tissue Coagulation and Their Value for the Planning and Monitoring of Laser- induced Interstitial Thermotherapy (LITT) [ J]. Magnetic Resonance in Medicine, 2003, 49:351 - 362
  • 10Ishimaru, A. Diffusion of Light in Turbid Media[J]. Applied Optics, 1989, 28(12) : 2210 -2215

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