期刊文献+

IGF-1R与肿瘤关系的研究进展 被引量:6

Development of study of the relation between IGF-1R and carcinoma
下载PDF
导出
摘要 复习相关文献 ,综述性报道IGF 1R与肿瘤关系的研究进展。资料表明 ,IGF 1R介导IGF 1的活性 ,促进细胞增殖、细胞转化、抑制细胞凋亡 ,与肿瘤的发生、发展、转移密切相关。提示IGF 1R作为分子靶位点将成为肿瘤基因治疗的一个新课题。
作者 肖君 孙维佳
出处 《中国普通外科杂志》 CAS CSCD 2004年第3期220-223,共4页 China Journal of General Surgery
  • 相关文献

参考文献36

  • 1[1]Samani AA, Brodt P. The receptor for the type I insulin-like growth factor and its ligands regulate multiple cellular functions that impact on metastasis[J].Surg Oncol Clin N Am,2001,10(2):289-312.
  • 2[2]Jones JI,Clemmons DR.Insulin-like growth factors and their binding proteins: biological actions[J].Endocrine Rer,1995,16(1):3-34.
  • 3[3]LeRoith D, werner H,Beitner-Johonson,et al.Molecular and cellullar aspects of the insulin-like growth fator 1 receptor[J].Endocr Rev,1995,16(2):143-163.
  • 4[4]Russell WE,Van Wyk JJ,Pledger WJ,et al.Inhibition of the mitogenic effect of plasma by amonoclonal antibody to somatomedin C[J].Proc Natl Acad Sci USA ,1984,81(8):2389-2393.
  • 5[5]Mulligan C, Rochford J, Denyer G, et al.Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1[J]. J Biol Chem,2002,277(45):42480-42487.
  • 6[6]Werner H, Woloschak M,Adamo M,et al.Developmental regulation of the rat insulin like growth factor 1 receptor gene[J]. Proc Natl Acad Sci USA,1989,86(19):7451-7455.
  • 7[7]Resnicoff M,Burgaud JL,Rotman HL, et al.Correlation between apoptosis, tumorigeneisis,and levels of insulin like growth factor 1 receptors[J]. Cancer Res,1995,55(17):3739-3741.
  • 8[8]Rubini M,Hongo A,Dambrosio C,et al.The IGF-1 receptor in mitogenesis and transformation of mouse embryo cells:role of receptor number[J].Exp Cell Res,1997,230(2):284-292.
  • 9[9]Valentinis B,Baserga R. IGF-I receptor signalling in transformation and differentiation[J].Mol Pathol,2001,54(3):133-137.
  • 10[10]Hellawell GO, Turner GD, DaviesDR, et al.Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease[J].Cancer Res, 2002 ,62(10):2942-2950.

二级参考文献3

  • 1Chang Yunchao,Cell Res,2000年,10卷,233页
  • 2Huo Y,J Cell Physiol,1998年,175卷,141页
  • 3Xu F,Br J Haematol,1997年,97卷,429页

共引文献12

同被引文献75

引证文献6

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部