急、慢性缺氧刺激对训练大鼠糖原和血糖的影响

The influence of acute or chronic hypoxia on training rat's glycogen and blood glucose

观察急、慢性缺氧刺激对训练机体糖原和血糖浓度的变化。以60只SD雄性大鼠为实验对象,人工制造缺氧φ(O2)14 5%(相当于海拔3000m),将实验动物随机分为安静3组和训练3组(分别为常氧对照组,急性缺氧组和4周慢性缺氧组),4周后对各组测定血糖、骨骼肌和肝脏糖原。结果显示,无论是安静组还是训练组,缺氧可使大鼠骨骼肌和肝脏糖原比常氧对照组显著或极显著性下降,但在训练组中慢性缺氧组骨骼肌和肝糖原含量仍比急性缺氧组高,血糖浓度却显著性的降低。提示慢性缺氧适应和运动训练可以提高机体糖原储备量,增强机体抗缺氧能力。

To investigate the influence of acute or chronic hypoxia on training rat's glycogen and blood glucose,Sixty male SD rats were divided into six group, three groups for still and three groups for training (the control for sea level, acute hypoxia, chronic hypoxia for four weeks), simulated altitude of 3 000 m for four weeks, blood glucose, skeleton muscle and liver glycogen were studied.Either still groups or training groups,exposes on altitude the content of glycogen is dramatically drop, but in the training groups,the group of chronic hypoxia the content of glycogen is still much more than that of the group of acute hypoxia, and the concentrations of blood glucose is dramatically drop.It can raise the content of glycogen,and can improve the ability to adapt altitude if chronic hypoxia and training are right.