摘要
应激性胃溃疡几乎存在于所有生命垂危的病人,如败血症、休克、烧伤、大手术后、严重的外伤等,并由它引起的胃肠道出血而导致病人的死亡比例,有升高趋势。目前对此病的防治,国内外尚无较为满意的方法。临床表明对本病的预防是非常重要的。大量研究证实,针灸可以治疗多种疾病,但针灸是否可以预防疾病研究甚少。所以进行电针预防大鼠应激性胃溃疡的研究是有较高的临床价值和理论意义。材料和方法应激性胃溃疡模型的制备:实验用Wistar大鼠,体重180～250克,雌雄各半,分成电针组和对照组。电针过程中。
The experimental Wistar rats were divided into two groups, the acupuncture group and the control group. Stress-induced gastric ulceration models were established through water immersion of restrained rats. The results are as follows. 1. The ulceration indices of the acupuncture group and the control group were 14.4±8(x±s) and 28.4±7.2 (P<0. 001). This indicates that electro -acupuncture has a protective effect on stress-induced gastrication in rats. 2. Smaller quantity of gastric juice, acidity and acid production in the gastric juice were seen in the electro -acupunctured mice than in those in the control group(P<0,05). This indicates that the protective effect of electro -acupuncture is connested with its inhibition on gastric secretion. 3. The Mg^(2+) ATP-ase activity observed in the electro-acupunctured mice was 67.3±10(index) while that in the control group it was 49.1±7(P<0.05). This indocates that Mg^(2+) ATP-ase is one of the protective factors of electro-aucpuncture.
