Theoretical Study on Effects of Salt and Temperature on Denaturation Transition of Double-stranded DNA

Theoretical Study on Effects of Salt and Temperature on Denaturation Transition of Double-stranded DNA

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摘要 We investigate the statistical mechanics properties of a nonlinear dynamics model of the denaturation of the DNA double-helix and study the effects of salt concentration and temperature on denaturation transition of DNA. The specific heat, entropy, and denaturation temperature of the system versus salt concentration are obtained. These results show that the denaturation of DNA not only depends on the temperature but also is influenced by the salt concentration in the solution of DNA, which are in agreement with experimental measurement.

作者 DONGRui-Xin YANXun-Ling PANGXiao-Feng JIANGShan LIUSheng-Gang

机构地区 SchoolofPhysicsScienceandInformationEngineering SchoolofPhysicalElectronics

出处《Communications in Theoretical Physics》 SCIE CAS CSCD 2004年第3期465-469,共5页 理论物理通讯（英文版）

基金 The project supported by the Doctoral Foundation of the Ministry of Education of China under Grant No.20010614005

关键词 DNA DENATURATION salt concentration DNA分子双螺旋结构变性作用盐浓度非线性动力学

分类号 Q523 [生物学—生物化学]

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Communications in Theoretical Physics

2004年第3期

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Theoretical Study on Effects of Salt and Temperature on Denaturation Transition of Double-stranded DNA

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