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Contraceptive effect of Curcuma longa (L.) in male albino rat 被引量：3

Contraceptive effect of Curcuma longa (L.) in male albino rat
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摘要 Aim: To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats. Methods: Rats were fed orally with Curcuma longa aqueous and 70 % alcoholic extract for 60 days (500 mg·kg-1· day-1). Results: A reduction in sperm motility and density was observed in both the treated groups. Conclusion: Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypo-thalamus pituitary axis and as a result, spermatogenesis is arrested. Aim: To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats. Methods: Rats were fed orally with Curcuma longa aqueous and 70 % alcoholic extract for 60 days (500 mg·kg-1· day-1). Results: A reduction in sperm motility and density was observed in both the treated groups. Conclusion: Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypo-thalamus pituitary axis and as a result, spermatogenesis is arrested.
作者 Purohit Ashok Bhagat Meenakshi
机构地区 Reproductive Physiology Section
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2004年第1期71-74,共4页 亚洲男性学杂志（英文版）
关键词 Leydig cells Curcuma longa seminiferous tubules ANTIANDROGENS SPERMATOZOA male contraception Leydig cells Curcuma longa seminiferous tubules antiandrogens spermatozoa male contraception
分类号 R285 [医药卫生—中药学]
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参考文献12

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  • 2Purohit A, Bhagat M. Contraceptive efficacy of Curcuma Ionga (L.) (70 % EtOH extract) with special emphasis on testicular cell population dynamics in male albino rats (Abst. 100). Proceedings of the Third Asian and Oceanic Congress of Andrology,24-27 May 2000, Chiba, Japan.
  • 3Bhagat M, Purohit A. Anti fertility of various extracts of Curcuma Ionga in male albino rats (Abst. 27). Proceedings of the National Symposium on Male Reproduction, 10-12 November 2001, Coimbatore, India.
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二级引证文献8

Asian Journal of Andrology
2004年 第1期

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