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人促甲状腺激素受体抗原决定簇的研究进展 被引量:5

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摘要 在环境和遗传因素基础上,机体免疫功能异常变化导致自身免疫性甲状腺疾病,促甲状腺激素受体抗体是其重要的自身抗体,它们属于异质性抗体,不同抗体诱发不同病理改变,每种抗体的相应抗原决定簇在促甲状腺激素受体上分布不尽相同,所致临床表现也迥然不同。确定不同抗体的相应抗原决定簇不仅有助于探讨其病理机制还具有临床诊治意义。
出处 《国外医学(内分泌学分册)》 2004年第2期116-118,共3页 Foreign Medical Sciences(Section of Endocrinology)
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参考文献19

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同被引文献67

  • 1兰玲,施秉银.促甲状腺素受体抗体检测的临床意义[J].国外医学(内分泌学分册),2005,25(1):42-44. 被引量:12
  • 2兰玲,施秉银.促甲状腺素受体抗体检测技术的回顾与展望[J].国外医学(内分泌学分册),2005,25(1):45-47. 被引量:11
  • 3郭淑红,赵舒景,王文英.TGAb、TPOAb检测在自身免疫性甲状腺疾病诊断中的意义[J].临床医学,2007,27(5):81-82. 被引量:13
  • 4葛勤敏,苏青.促甲状腺激素受体的裂解和脱落[J].上海交通大学学报(医学版),2007,27(3):354-356. 被引量:2
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