摘要
囊泡单胺转运体 (vesicularmonoaminetransporter ,VMAT)也称为囊泡单胺转运蛋白 ,介导单胺类递质在突触囊泡中的转运。近年来其分子结构在体内的分布及生理功能已被初步阐明 。
出处
《中国临床神经科学》
2004年第1期89-92,共4页
Chinese Journal of Clinical Neurosciences
参考文献20
-
1Lee WY,Chang JW,Nemeth NL,et al .Vesicular monoamine transporter-2 and aronatic L-amino aeid decarboxylase enhance dopamine delivery after L-3,4-dihydroxyphenylalanine administration in Parkinsonian rats[J].J Neurosci,1999,19:3266-3274.
-
2Staal RG,Sonsella PK.Ininibiton of brain vesicular monoanine transporter (VMAT2) enhanced 1-methyl-4-phenylpyridinium neurotoxicity in vivo in rat striata[J].J Pharmacol Exp Ther,2000,293:336-342.
-
3Staal RG, Hogan KA, Liang CL, et al. In vivo studies of strialal vescles containing the vesicular monoanine transporter (VMAT2):rat versus mouse difference in sequestuation of 1-methyl-4-phenylpyridinium[J].J Pharacol Exp Ther,2000,293:329-325.
-
4Fumagalli F, Gainetdinov RR, Wang YM, et al. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. Neurosci, 1999,19:2424-2431.
-
5Wilson JM, Levey AL, Rajput A, et al. Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson 's disease [ J ]. Neurology, 1996,47: 718-726.
-
6Miller GW, Erickson JD, Perez JT, et al. lmmunochemical analysis of vesicualr monoamine transporter (VMAT2) protein in Parkinson' s disease [J]. Exp Neurol, 1999,156:138-148.
-
7Hogan KA, Staal RG, Sonsalla PK. Analysis of VMAT2 binding after methamphetamine or MTP treatment:disparity between homogemates and vseicle preparations [ J ]. J Neurochem, 2000,74 ( 5 ) : 2217 -2220.
-
8Ito Y,Fujita M,Shimada S,Comparson between the decrease of dopamine transporter and that of L-DOPA uptake for detection of earily to advanced stage of Parkinson's disease in animal models[J].Synapse,1999,31:178-185.
-
9Gainetdinov RR,Fumagalli F,Wang YM,et al.The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesiclar monoamine transporter[J].Neuroscience,1998,84:1177-1185.
-
10Nirerberg MJ, Liu Y, Peter D, et al. The vesicular monoamine transporter 2is present in small synaptic vesicles and preferentially loealixes to large dense core vesicles in rat solitary tract nuclei [ J ]. Proe Natl Acad Sei USA, 1995,92 : 8773-8777.
同被引文献16
-
1吴鸣,金松华,沈定,张佩华,石桂枝.儿童病毒性脑炎脑脊液肿瘤坏死因子和神经元特异性烯醇化酶的变化[J].实用中西医结合临床,2007,7(1):4-5. 被引量:7
-
2吴恩惠,李海生,赵彤,樊俊蝶,马鑫,熊雷,李伍举,朱玲玲,范明.低氧对人骨髓间充质干细胞基因表达谱的影响[J].生理学报,2007,59(2):227-232. 被引量:1
-
3Bartholomew A, Sturgeon C, Siatskas M, et al. Mesenchymal stem ceils suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol, 2002, 30:42-48.
-
4Mazhari R, Hare JM. Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche. Nat Clin Pract Cardiovasc Med, 2007, 4:21-26.
-
5Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxie gradients through H IF21 induc- tion of SDF-1. Nat Med, 2004,10:858-864.
-
6Passeri S, Nocchi F, Lamanna R, et al. Isolation and expansion of equine umbilical cord-derived matrix ceils (EUCMCs). Cell Bi- oI Intern, 2009, 33: 100-105.
-
7Ren HY, Cao Y, Zhao Q J, et al. Proliferation and differentiation of bone marrow stromal ceils under hypoxic conditions. Biochem Biophy Res Commun, 2006, 347 : 12-21.
-
8Csete M. Oxygen in the cultivation of stem cells. Ann NY Acad Sci, 2005, 1049:1-8.
-
9Wang YS, Sun A J, Xue JJ, et al. Bone marrow derived stromal cells modified by adenovirus-mediated HIF-1 a double mutant pro- tect cardiac myocytes against CoC12-induced apoptosis. Toxicol Vitro,2009,23 : 1069-1075.
-
10Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Cord blood ge- nomic analysis highlights the role of redox balance. Free Rad Biol Med, 2010, 49 : 992-996.
二级引证文献4
-
1卜欠欠,陈慧中,曾慧兰,覃永亮,钟启,李阳,刘宏伟,苏泽轩.尼古丁对人脐带间充质干细胞氧化应激的影响[J].暨南大学学报(自然科学与医学版),2012,33(4):362-366. 被引量:2
-
2曾慧兰,卜欠欠,陈慧中,覃永亮,李阳,柏小芬,钟启,余泮熹,刘宏伟,刘革修,苏泽轩.尼古丁对人脐带间充质干细胞增殖和迁移的影响[J].中国病理生理杂志,2013,29(5):778-783. 被引量:9
-
3王劲松,胡家,王松灵.人乳牙牙髓干细胞和恒牙牙髓干细胞的蛋白质组学比较[J].北京口腔医学,2013,21(5):249-253. 被引量:2
-
4王天生,张建军.人端粒酶反转录酶基因修饰脐带间充质干细胞移植治疗急性肾损伤[J].中国组织工程研究,2015,19(23):3686-3691.
-
1杨娇龙,黄金莎,王涛.Ⅱ型囊泡单胺转运体与帕金森病[J].中华神经科杂志,2015,48(2):149-152.
-
2田向阳,孙兴珍,赵卫东,陈泉,丁新生,董海蓉,闵敏.囊泡单胺转运体在脑组织中的分布特征与帕金森病相关性的研究[J].山西医药杂志(上半月),2009,38(10):896-898. 被引量:1
-
3田向阳,丁新生,闵敏,孙兴珍.囊泡单胺转运体在人胚胎脑组织中的分布特征及其与帕金森病的关系[J].临床神经病学杂志,2008,21(4):270-272. 被引量:2
-
4张克忠,蒋雨平,徐星.Lactacystin对大鼠纹状体DAT和VMAT2蛋白表达的影响[J].中国临床神经科学,2007,15(2):143-147. 被引量:1
-
5任今鹏,任惠民,蒋雨平.百草枯对小鼠黑质纹状体通路囊泡单胺转运体2的影响[J].中国临床神经科学,2004,12(4):333-336. 被引量:3
-
6王铭维,马晓伟,刘力,顾平,耿媛,崔冬生.利血平对转染VMAT_2基因的CHO细胞抵抗鱼藤酮及多巴胺毒性作用的研究[J].山东大学学报(医学版),2009,47(7):1-3.
-
7王铭维,刘力,顾平,崔冬生,王彦永.CHO细胞中VMAT_2的鉴定及应用[J].河北医科大学学报,2008,29(6):801-803.
-
8董海蓉,叶民,丁新生.帕金森病黑质多巴胺神经元的凋亡与其发病机制(英文)[J].中国临床康复,2004,8(4):758-759. 被引量:6
-
9张京钟,余爽,赵春礼,段春礼,徐群渊.帕金森病基因治疗的理论:VMAT_2基因的表达及其对MN9D细胞多巴胺代谢的影响[J].中国临床康复,2004,8(4):667-669. 被引量:1
-
10刘振国.分子影像学在帕金森病临床中的应用价值[J].中华神经科杂志,2010,43(6):385-387. 被引量:3