结直肠癌前哨淋巴结活检的研究进展

Advances in Sentinel Lymph Node Biopsy in Colorectal Cancer

目的 了解前哨淋巴结 (SLN)活检技术在结直肠癌领域的应用现状。方法 复习国外近 5年的文献并加以综述。结果 SLN状态可以准确预测结直肠癌区域淋巴结群的肿瘤转移情况 ,对SLN行集中、细致的分析有助于发现传统病理学检查遗漏的微转移灶 ,从而使部分患者肿瘤分期上调。结论 结直肠癌SLN活检是一种切实可行的技术 ,有望为临床判断区域淋巴结群受累状况提供一种新的手段 ,从而有助于更准确的肿瘤分期。

Objective To understand the current research status of sentinel lymph node (SLN) biopsy in colorectal cancer. Methods Literatures about the application of SLN biopsy in the field of colorectal surgery were collected and reviewed.Results The results of SLNs biopsy accurately reflected the status of the nodal basin. Focused examination of the SLNs could identify micrometastases that might otherwise had been missed by standard histopathological analysis, thus upstaged this group of patients.Conclusion SLN biopsy represents a new and effective technique to predict the tumor status of regional lymph nodes, which offers a potential alternative to improve the accuracy of tumor staging in colorectal cancer.