荷瘤小鼠后爪部分证的标志图谱

Signing Atlases of Zheng on Hind Paws in Tumor-bearing Mice

辨证论治寻求最佳个体化治疗是中医药的精髓 ,其前提是通过望闻问切进行辨证。对于小鼠这样小的动物实验 ,如何辨证一直是困扰中医药辨证论治实验研究的一大难题。本文报道了我们在既往探索荷瘤小鼠非创伤性辨证论治的基础上 ,进一步通过对小鼠后爪显微镜放大、数码相机拍摄的不同证的代表性图谱 ,并采用图像软件计算爪色的RGB分量值 ,进行初步望色的定量。结果表明放大后的小鼠爪有着丰富的变化 ,可以明显反映出不同的证 ,其色的变化可以通过其国际标准的RGB分量值定量 ,从而可以实现小鼠的辨证。

It is the essence of TCM to seek best individualized therapy through syndrome differentiation based on inspection,auscultation-plfaction,inquiry and palpation.But it is a long-standing frustration for experimental research of TCM syndrome differentiation to differentiate subjects' syndromes as mice.This essay reports our quantitative analysis on inspection based on former exploration syndrome differentiation of mice transplanted with tumor.Typical atlas of syndromes at all level of hind paws mice are recorded by magnified digital photoes.And RGB value are obtained by counting these photoes with softwares.The results manifestate that mouse paws show plentiful divergence of syndromes at all level.The syndromes differentiation of mice can be realized by determining international standard RGB value.