北京地区近4年肠道病原菌感染的特点

Features of enteric pathogenic bacteria in Beijing in recent 4 years

目的监测北京地区肠道致病菌的组成及耐药状况,为本地区的流行病学研究及临床合理用药提供依据。方法通过常规大便培养,筛出致病菌后经生化及血清学进一步鉴定到种、群或血清型。结果肠道病原菌分布以男性为主,儿童和青年发病为多,7月～9月为腹泻发病高峰。病原以志贺菌属居首位,其次是弧菌。各菌属对抗生素的敏感率有差异。结论北京地区感染性腹泻的病原种类繁多,有性别、年龄、季节的分布特点,耐药性不同,应重视监测。

To monitor the distribution and resistance of enteric pathogenic bacteria in Beijing to offer the data for guiding epidemiological study and clinical treatment. Methods The enteric pathogenic bacteria isolated from patients in Beijing were cultured and identified to species, groups and serotypes with biochemical and serological tests. Then their susceptibility to antimicrobial agents was determined. Results The distribution of these bacteria was dominant in male and young patients and children. It peaked in July and September. Shigellae spp and Vibrio spp were the main pathogenic bacteria in the intestinal tract. Various bacteria had different sensitivities to different antimicrobial agents. Conclusions There are many species of enteric pathogenic bacteria causing infectious diarrhea in Beijing. Their distribu- tion is significantly related to sex, age and season. Meanwhile, the rates of their resistance to different antimicrobial a- gents are different. Therefore, surveillance of the bacteria should be emphasized.