摘要
目的 :建立复方人参注射液 (人参、陈皮等 )的核磁共振指纹图谱 ,探索质量控制的新方法。方法 :运用核磁共振技术对复方人参注射液的中间体和成品进行指纹图谱研究 ,探索简便易行的指纹图谱分析方法。结果 :通过对中间体和注射液的图谱相似度分析 ,表明工艺流程稳定 ,重现性良好。结论 :核磁共振技术可以作为中成药指纹图谱研究的辅助方法以控制中药质量。
AIM: To establish the NMR fingerprint of the “Compound Renshen Injection”(Radix Ginseng,Pericarpium citri Reticulata,etc),including intermediate and injection so as to control the quality of the injection. METHODS : NMR was applied to analyze intermediate and injection,establishing the fingerprint of them by contrasting and analyzing the graphs. RESULTS : The fingerprint of intermediate and injection was established,further more,the fingerprint of them showed an excellent recurrence and stabilization. CONCLUSION : This method of NMR has the advantages of accuracy and good repeatability and can be used for the quality control of Compound Renshen Injection.
出处
《中成药》
CAS
CSCD
北大核心
2004年第3期173-174,共2页
Chinese Traditional Patent Medicine
基金
江苏省现代中药制剂工程技术研究中心资助项目 (2 0 0 0 3 14 )
关键词
核磁共振
指纹图谱
复方人参注射液
人参
陈皮
NMR
fingerprint
Compound Renshen Injection
Panax Ginseng Citrus Reticulata Blanco (CRB)