摘要
目的 :建立桔远止咳片 (桔梗、远志 ,盐酸麻黄碱等 )中盐酸麻黄碱的含量测定方法。方法 :高效液相色谱法 ,采用ODS柱 ,以乙腈 - 0 .0 2mol·L-1磷酸二氢钾溶液 (含 0 .2 %三乙胺 ,磷酸调 pH2 .7) (5∶10 0 )为流动相 ;检测波长为 2 10nm。结果 :盐酸麻黄碱线性范围为 0 .2～ 1.6 μg ,r=0 .9999,平均回收率为 97.7% ,RSD为 0 .5 8%。 结论 :方法简便可行、重现性好 ,适用于该制剂的质量控制。
AIM: To establish a method for the determination of ephedrine hydrochloride in Juyuanzhike Tablets (Radix Platycodonis,Radix Polygalae,ephedrinelydrochloride,etc.). METHODS :Ephedrine hydrochloride in Juyuanzhike Tablets were determined by HPLC. RESULTS : The linear range was 0.2～1.6 μg,r =0.9999.The average recovery was 97.7% and RSD was 0.58%,respectively. CONCLUSION : The method is simple,feasible and reproducible. It can be used for the quality control of Juyuanzhike Tablets.
出处
《中成药》
CAS
CSCD
北大核心
2004年第3期201-203,共3页
Chinese Traditional Patent Medicine
