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嗅觉障碍与阿尔茨海默病的研究进展 被引量:2

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摘要 阿尔茨海默病(Alzheimer’s disease,AD)患者嗅觉系统病理改变与皮层退行性变的损害程度完全一致,而且嗅觉系统发生病变在时间上早于皮层病变。AD患者均有不同程度的嗅觉缺损,表现为嗅觉阈升高,嗅觉识别和嗅觉记忆减退。嗅觉缺损可见于AD的前期。是AD早期诊断的重要指标。嗅觉系统与大脑皮层许多部位有广泛联系,药物经嗅觉通路能被转运到脑内多个部位,通过嗅觉通路有可能找到治疗AD有效药物。
出处 《国外医学(神经病学.神经外科学分册)》 2004年第1期87-90,共4页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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