尿激酶灌注引流治疗脑室出血的临床观察

The clinical observation of urokinase perfusion drainage in treatment of intraventricular hemorrhage

目的 探讨尿激酶灌注治疗脑室出血的观察要点 ;方法 将 5 8例患者随机分为A、B两组 ,A组 2 8例 ,B组 3 0例。均在尿激酶灌注后进行夹管 ,A组采用夹管 2h开放引流管 ,B组采用夹管 4h开放引流管 ,对患者的夹管时间 ,引流液的性状、颜色及病情进行观察 ;结果 两组患者的出血部位、年龄、病情无显著性差异 ,从夹管时间、出血吸收时间对比 ,经X2 检验p <0 .0 5 ,有显著性差异 ,即夹管 4h优于夹管 2h ;结论 尿激酶灌注引流能缩短脑室积血的清除时间 ,使患者的病情缩短 ,减少并发症的发生 ,促进患者早日康复 ,提高患者的生命质量。

Objective To explore the observation point of urokinase perfusion drainage in treatment of intraventricular hemorrhage.Methods 58 cases of intraventricular hemorrhage patients were divided randomly into group A and group B, 28 cases in group A and 30 cases in group B. All patients were closed tube after urokinase perfusion, opening the drainage tube after 2 hours in the group A, then 4 hours in the group B. The character and color of drainage, the time of closing tube and state of illness were observed in the two groups.Results The difference in the hemorrhage site, ages and symptoms were no significant in two groups. Then the difference was significant in the time of closing tube and absorption time of hemorrhage with X 2 test, the closing tube 4 hours was better than 2 hours (P<0.05). Conclusions The urokinase perfusion drainage can shorten the time of clearance of intraventricular hematoma and the state of illness, reduce the occurrence of complication, and improve the early recovery and life quality of patients.