小柴胡汤口服液药效作用的研究

Study on Pharmacodynamic Action of Xiaochaihu Oral Liquid(Radix Bupleuri)

观察了小柴胡汤口服液的主要药理作用。研究表明,小柴胡汤口服液有显著抑制角叉菜胶诱发的大鼠踝关节水肿(p<0.05),保护四氯化碳所致的大鼠急性肝功能损害,有极显著降低血清SGPT及LDH的作用(P<0.01)。对家兔发热反应也有较好的抑制作用。此外,小柴胡汤口服液对小鼠兔疫反应也有一定的增强作用,可促进小鼠碳粒廓清速率,提高血清溶血素水平及增强鸡红细胞所致的迟发性过敏反应。

In this experiment,Xiaochaihu Oral Liquid was found to possess marked functions of inhibition on hydrops of rat articulatio talocruralis(p<0.05)induced by Carrageenin,of protection on acute liv- er function damage of rat(caused by carbon tetrachloride),of depression of SGPT and LDH(p<0.01) and inhibition of the fever reaction of rabbit.In addition,it enhanced immunity reaction of mice promoted carbon particle clearence of mice and raised the level of serum hemolysin and enhanced de- layed anaphylaxis reaction induced by chicken red cells.