急性有机磷农药中毒早期定量分析血胆碱酯酶变化与临床中毒程度关系的探讨

Relationship between Quantitative Cholinesterase Analysis and Toxicosis Degree during Early Period of Acute Organophosphorous Poisoning

目的:探讨急性有机磷农药中毒早期定量分析血胆碱酯酶变化与临床中毒程度的关系。方法:将本院195例急性有磷农药中毒患者,按临床中毒程度分轻、中、重3组,同时以定量分析法及纸片法检测血胆碱酯酶活性,并与临床中毒程度比较,分析两者的差异。结果:定量分析法在临床符合程度上优于纸片法(P<0.05)。结论:急性有机磷农药中毒早期定量分析法在检测血胆碱酯酶变化与临床中毒程度关系上较纸片法优胜、准确,但在临床工作中仍有必要将中毒症状与血胆碱酯酶检测相结合。

Objective: To investigate the relationship between the change of quantilative eholinestetase analysis and the severity of AOPP. Methods: Through quantilative choliriesterase analysis in 195 patients of AOPP, to compare the change of cholinesterase in different degree patients of AOPP. Result: Quantilative cholinesterase condidtence changed according to the toxicosis degree. Conclusion: Quantilative cholinesterase analysis was superior in reflecting toxicosis degree.