摘要
胶原诱导性关节炎是应用较广泛的人类风湿性关节炎动物模型 ,二者在发病机制及病理学改变上极为相似。近年来研究证实激活的某些T细胞在胶原诱导性关节炎的发病过程中起着重要作用 ,尤其在疾病的起始阶段 。
Collagen-induced arthritis (CIA) is a widely-used experimental animal model o f human rheumatoid arthritis(RA) which shares certain features with RA, such as in pathogenesis and pathology. Recent research demonstrates that some activated T cells are critical to the development of CIA, especially during the initial ph ase. All suggests that CIA is kind of dominant T cell-mediated autoimmune disea se.
出处
《中国实验动物学报》
CAS
CSCD
2004年第1期53-56,共4页
Acta Laboratorium Animalis Scientia Sinica
基金
北京市教委科技发展计划项目(编号 2 0 0 2KJ0 85)