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小鼠胚胎干细胞体外发育分化模型 被引量:2

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摘要 胚胎干细胞 (Embryonicstemcell ,EScell)是多潜能性细胞 ,它在体外既可维持不分化而无限增殖 ,又能参与胚胎发育分化为各种类型细胞和组织而形成器官 ;小鼠ES细胞可供的数量大、在体外培养条件可进行精确调控、实验比较经济加上现代基因及其他生物操作等技术 ,因此小鼠ES细胞体外发育分化系统被广泛地作为模型系统加以利用。小鼠ES细胞体外发育分化研究为推动其他哺乳类动物以及人的ES细胞研究 ,从而将更好地进行细胞、组织工程实验为人类细胞组织和基因治疗服务创造了有利条件。本文将ES细胞体外发育分化情况加以概述 。
出处 《中国实验动物学报》 CAS CSCD 2004年第1期57-63,共7页 Acta Laboratorium Animalis Scientia Sinica
基金 安徽省教育厅教育基金( 2 0 0 1kj173)
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同被引文献27

  • 1刘民,李柏青.小鼠胚胎成纤维细胞的分离、扩增和抑制[J].中国实验动物学杂志,2002,12(4):215-219. 被引量:30
  • 2高舒平,时伟红,秦英,董婉维,王太一.用于胚胎干细胞分离培养的饲养层的制作[J].中国实验动物学杂志,2000,10(2):78-81. 被引量:7
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