脑梗塞患者血浆TXB_2、6-酮-PGF_1α和血小板内cAMP、cGMP含量的测定

The measurement of plasma TXB_2, 6-keto-PGF_(1α) and the content of cAMP, cGMP in platelets in the patients with cerebral infarction

测定220例脑梗塞患者血浆TXB_2;6—酮-PGF_(12)和血小板内cAMP;cGMP的含量,结果TXB_2;cGMP增高,6-酮-PGF_(1a)、cAMP降低,较之单一测定血浆内的含量能更直接而精确地反映血管壁状态与血小板功能。

The measurement of plasma TXB_2, 6-keto-PGF_(1α) and the content of cAMP, cGMP in platelets of 220 patients with cerebral infarction and those of the control group(50) determined in our hospital. The results showed that the quantities of TXB_2, cGMP were significantly increased and 6-keto-PGF_(1α), cAMP were markedly reduced. These may show the damage state of vessel wall and the function of platelet directly.