摘要
本文比较10μg三个批号国产HB-Vac的4年免疫持久性,发现在同一年龄组免疫持久性在性别上无差异(P>0.05),但在临界保护率(S/N≥2.1)和有效保护率(S/N≥10)幼儿组明显高于成年组(P<0.05)。鉴于幼儿初免4年后有效保护率下降到60％以下,建议HBVac加强免疫可在初免3—4年进行。
The immune persistance of three batches of domestic Hepatitis B Vaccine at a dose of 10μg were studied for four years. The results showed that in the same age group there was no difference in immune persistance by sex. The critical protective rate and effective protective rate were higher in the infant groups than in the adult groups. The difference has statistical significance (P<0.05). The protective efficacy of primary vaccination in the infants group dropped to lower than 60 per cent after four years. This suggested that a booster injection need 3～4 years after the 3-doses prlmary vaccination.
出处
《中国病毒学》
CSCD
1992年第3期272-275,共4页
Virologica Sinica
