角膜缘上皮移植联合丝裂霉素C治疗翼状胬肉

Limbal epithelial autograft transplantation combined mitomycin C application for the treatment of pterygium

目的 探讨自体角膜缘上皮移植联合丝裂霉素C在降低翼状胬肉术后复发率方面的作用。方法 常规方法切除翼状胬肉后 ,先用丝裂霉素C棉片贴敷 ,然后自体角膜缘上皮移植 ,覆盖巩膜暴露区。结果 术后观察 6～ 2 2月 ,手术 42眼 ,有 2眼复发 ,复发率为 4.8%。并发症有异物感、流泪 4眼 ( 9.5 % ) ,结膜创口愈合延迟 2眼 ( 4 .8% ) ,浅层点状角膜炎 1眼( 2 .4% ) ,干眼症 2眼 ( 4 .8% )。结论 自体角膜缘上皮移植联合丝裂霉素C能有效地降低翼状胬肉术后复发率 ,手术方法简单、安全、并发症少。

Objective To investigate the effects of limbal epithelial autograft transplantation combined mitomycin C application in preventing the recurrence of pterygium. Methods After cut of pterygium,the sclera was covered by a tampon with 0.4 mg/mL mitomycin C for 3 minutes and washed by physical solution,then limbal epithelial autograft was transplanted to the area.The follow-up time was 6-22 months. Results For all of the 42 eyes,pterygium recurred in 2 eyes(4.8%).The complications included foreign body sensation,tearing,delayed conjunctival healing,punctate keratitis,and dry eye syndrome.Conclusion Limbal epithelial autograft transplantation combined mitomycin C application can effectively prevent the recurrence of pterygium.It is simple,safe and has lower complications.