人体肺支气管树内的气流分布研究

Air Distribution in the Bronchial Tree of Human Lungs

在 Weible的人体肺支气管树统计数据的基础上 ,参照肺解剖图形 ,运用流体网络理论建立支气管树在前 5～ 7级为不对称分叉 ,后面的分级为对称分叉的三参数集中参数模型。采用 GEAR算法求解常微分方程组 ,探讨在正常呼吸过程中气体在肺支气管树内不同分段的压力流量分布。在此基础上探讨了支气管局部受阻时 ,肺支气管树内不同部位的压力和流量的分布状况 ,并进行了比较。该模型对认识肺支气管树在生理。

A three element model of lumped parameter based on the statistic data of Weible's symmetric model and on the reference anatomic figures of the bronchial tree of the lungs has been proposed using the fluid network theory. It was assumed that the upper five or seven generations of the twenty four generations of the respiratory airway are asymmetric, while the rest are symmetric. GEAR method was used to solve the ordinary differential equations. The pressure and flow rate distributions in different positions of the lungs during normal respiration and partial bronchial obstruction were compared, respectively. This model has great significance in finding out the air distribution in the human bronchial tree under various physiological and pathological conditions.