癫痫发作预测研究的新进展

The Progress in Epileptic Seizure Prediction

癫痫是一种慢性神经系统紊乱的疾病 ,发病率约为 0 .5 %～ 2 % ,其中 10 %～ 5 0 %的患者药物治疗无效或不适于进行手术。对这些患者来说 ,不可控制的发作是造成残疾甚至死亡的主要原因。因此 ,研究癫痫发作的预测方法 ,使患者或医生提前采取预防措施 ,减小发作时对病人的伤害是十分有意义的。本文介绍了癫痫发作预测的可行性 ,研究现状。

It is estimated that epilepsy, a chronic disorder of the nervous system, affects about 0.5% 2% of the population and about 10% 50% do not respond well to current antiepileptic medications and may not be candidates for surgery. For these patients, the unpredictability of seizure onset is a major cause of disability and mortality. Therefore, anticipation of an imminent seizure would be beneficial to patients because it could provide time for the application of preventive measures to keep the risk of seizure to a minimum. This paper reviews the feasibilities, the progress, existing problems and possible applications in the field of epileptic seizure prediction.