CR1在红细胞免疫中的研究进展

The study improvement of complement receptor type 1 in the function of red cell immune adhesion

目的总结Ⅰ型补体受体(CR1,CD35)在红细胞免疫中的研究进展。方法通过阅读有关文献,了解红细胞CR1在红细胞免疫研究中的地位。结果CR1分子有其特定的编码基因、分子结构、生物学特性,广泛参与体内免疫复合物(IC)的清除。结论CR1是红细胞执行免疫功能的主要分子基础。

Objective:We summarize the studies of complement receptor type 1(CR1)in the function of red cell immune adhesion(RCIA).Method:To investigate the role of CR1 on erythrocytes in the function of RCIA through studying the involved articles.Result:In addition to the special coding sequence,molecular structure and biological specificity of the CR1,It play a important role in the clearance of circulating immune complexes from the circulation to the reticuloendothelial system,including the liver and spleen.Conclusion:CR1 is one of the molecular basis of the function of RCIA.