补益胶囊中黄芪甲苷的提取工艺研究

Study on Optimum Preparation Process of Astragaloside Ⅳ in Buyi Capsules by Orthogonal Design

目的 :考察补益胶囊中黄芪甲苷的最佳提取工艺。方法 :通过正交实验 ,以干膏收率和黄芪甲苷总量为指标 ,考察加水量、煎煮时间、煎煮次数对提取效果的影响。结果 :补益胶囊中黄芪的最佳提取工艺为加水 12倍 ,煎煮 2次 ,3 h/次。结论 :最佳工艺稳定 。

Objective:To optimize the preparation process of astragaloside Ⅳ in Buyi Capsules.Methods:The optimum preparation process was investigated by L 9(3 4) orthogonal design as the astragaloside Ⅳ and total mount of dry ointment content index. The chief factors influencing the extraction efficiency were as follows:times of added water, the time of extraction and times of boiling.Results:The optimum technical condition:added 12 times water, cook 3 hours and 2 times.Conclusion:Astragaloside Ⅳ content was high. The method is reliable, accurate and easy to operate. It was up to the mustard.