比气道传导率测定在症状不典型哮喘患者中的应用

Measurement of specific airway conductance in asthmatic patients with atypical symptoms

目的 探讨比气道传导率测定在症状不典型哮喘患者支气管舒张试验中的应用。方法 应用体积描记仪对 4 5例症状不典型哮喘患者进行气道阻力 (Raw)、比气道传导率 (sGaw)、1秒钟用力呼气容积 (FEV1 )测定 ,随后给予吸入沙丁胺醇 ,观察肺功能指标的变化。结果 吸入沙丁胺醇前后sGaw、Raw、FEV1 差异显著 ,均有统计学意义。

Objective To investigate the sensitivity of specific airway conductance during bronchial dilation test of asthmatic patients with atypical symptoms.Methods The airway resistance(Raw),specific airway conductance(sGaw) and forced expiratory volume in one second(FEV 1) were measured using body plethysmograph,and inhaled β 2 adrenoceptor agitating drugs(such as Salbutamol Aerosol) in 45 asthmatic patients with atypical symptoms.Results There was significant difference in Raw,sGaw and FEV 1 after inhaltion of Salbutamol Aerosol(P< 0.01).Conclusion sGaw can be used as a new method of investigation on airway reactivity.