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肿瘤特异增殖病毒的研究进展

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摘要 经转录调节修饰的肿瘤特异增殖病毒可特异性地杀伤肿瘤细胞 ,具有临床治疗肿瘤的潜在价值 ,是近年来肿瘤研究的热点之一 ,并取得了很大的进展 。
出处 《国外医学(肿瘤学分册)》 2004年第3期189-192,共4页 Foreign Medical Sciences (Cancer Section)
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  • 1Kurihara T, Brouth DE, Kovesdi I, et al. Selectivity of a replication-competent adenovirus for human breas carcinoma cells expressing the MUC-antigen. J Clini Invest, 2000, 106(6) : 763-771.
  • 2Steele TA. Recent development in the virus therapy of cancer.Proc Soc Exp Biol Med, 2000, 223(2) : 118-127.
  • 3Demers GW, Johnson DE, Tsai V, et al. Pharmacologic indicators of antitumor efficacy for oncolytic virotherapy. Cancer Res, 2003,63(14) :4003-4008.
  • 4Biederer C, Ries S, Brandts CH, et al. Replication-selective vires to cancer therapy. J Mol Med, 2002, 80(3) : 163-175.
  • 5Johnson L, Shen A, Boyle L, et al. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell, 2002, 1(4) :325-337.
  • 6Freytag SO, Rogulski KR, Paielli DL, et al. A novel three-pronged approach to kill cancer cells selectively, concomitant vrial, double suicide gene, and radiotherapy. Hum Gene Ther, 1998, 9 ( 9 ) :1323-1333.
  • 7Heise C, Hermiston T, Johnson L, et al. An adenovirus E1A mutant than demonstrates potend and selective systenlic anti-tumoral efficacy. Nat Med, 2000, 6(10):1134-1139.
  • 8Li Y, Yu DC, Chen Y, et al. A hepatocellular carcinoma-specific adenovirus vaiant, CV 890, eliminates distant human liver tumors in combination with doxorubicin. Cancer Res, 2001, 61( 17):6428-6436.
  • 9Hallenbeck PL, Chang YN, Hay C, et al. A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellar carcinoma. Hum Gene Ther, 1999, 10(10) : 1721-1733.
  • 10Takahashi M, Sato T, Sagawa T, et al. E1B-55k-deleted adenovirus expressing E1A-13s by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor. Mol Ther, 2002, 5(5 Pt 1 ):627-634.

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