1Nephew KP, Huang TH. Epigenetic gene silencing in cancer initiation and progression. Cancer Lett,2003, 190(2):125-133.
2Heanev A P, Melmed S. New pituitary oncogenes. Endoer Relat Cancer, 2000,7 ( 1 ) ; 3-15.
3Reik W, Murrell A. Genomic imprinting. Silence across the border.Nature, 2000,405 (6785) : 408-409.
4Lee IT, Davidow LS, Warshawsky D. Tsix, a gene antisense to Xist at the X-inactivation centre. Nat Genet, 1999,21 ( 4 ) : 400-404.
5Wong YF, Chung TK, Cheung TH, et al. Methylation of p161NK4A in primary gynecologic malignancy. Cancer Lett, 1999, 136(2):231-235.
6Strathdee G, Appleton K, llland M, et al. Primary ovarianearcinomas display multiple methylator phenotypes involving known tumor suppressor genes. Am J Pathol,2001,158(3) : 1121-1127.
7McCluskey LL, Chen C, Delgadillo E, et al. Differences in p16 gene methylation and expression in benign and malignant ovarian tumors. Gynecol Oneol, 1999, 72 ( 1 ) : 87-92.
8Brown I, Milner BJ, Rooney PH, et al. Inactivation of the p16INK4A gene by methylation is not a frequent event in sporadic ovarian carcinoma. Oneol Rep,2001, 8(6) : 1359-1362.
9Yoon JH, Dammann R, Pfeifer GP. Hypennethylatlon of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas.Int J Cancer, 2001, 94(2) :212-217.
10Strathdee G, MacKean Mj, Illand M, et al. A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer. Oncogene, 1999, 18 ( 14 ) : 2335-2341.
同被引文献38
1Watanabe T,Nakamura M,Yonekawa Y,et al.Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas [J].Acta Neuropathol(Berl) ,2001,101 (3) :185 - 189.
2Bird AP.DNA methylation de novo[J].Science,1999,286 (5448):2287- 2288.
3Liggett WH Jr,Sidransky D.Role of the p16 tumor suppressor gene in cancer[J].J Clin Oncol,1998,16(3):1197 - 1206.
4Rocco JW,Sidransky D.p16 (MTS-1/CDKN2/INK4a) in cancer progression[J].Exp Cell Res,2001,264(1) :42 - 55.
5Jin X,Nguyen D,Zhang WW,et al.Cell cycle arrest and inhibition of tumor cell proliferation by the p16INK4 gene mediated by an adenovirus vector[J].Cancer Res,1995,55:3250 - 3253.
6Nephew KP,Huang TH.Epigenetic gene silencing in cancer initiation and progression [J].Cancer Lett,2003,190 (20):125 -133.
7Gonzalez-Zulueta M,Bender CM,Yang AS,et al.Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing[J].Cancer Res,1995,55(20) :4531 - 4515.
8Narayan G,Arias-Pulido H,Nandula SV,et al.Promoter hypermethylation of p16INK4A:disruption of Fanconi AnemiaBRCA pathway in cervical cancer[J].Cancer Res,2004,64(9):2994 - 2997.
