矽肺患者血液流变学与动脉血气分析

A Study on the Hemorheology and Blood Gas in Patients of Silicosis

本研究测定了67例Ⅱ、Ⅲ期矽肺患者的血液流变学和动脉血气。结果提示,不同期别和不同氧分压的粘度特性(ηp、η0.312、η51.2、A.I、CHT)和粘弹特性(η′、η″、G′)有显著差异。η0.512、η52.2、A·I、η′、η″、G′与PaO_2呈负相关,与PaCO_2和pH无相关关系。ηp可能与血液中免疫球蛋白有一定关系。作者认为提高血氧对改善矽肺患者血液流变学异常有一定帮助。

Using the low-shear-30 ginus rheometer and corining-168 blood gas rheometer, we tested hemorheology and blood gas of 67 patientsof silicosis. The results showed that viscosity(η_p.η_(0.512),η_(51.2) A.I and CHT) and viscoelastricity (η′.η″. G′) increased with increasinggrades of silicosis and decreasing PaO_2. Theerlationship between (η_(0.512).η_(51.2) A.I η′,η″,G′) and PaO_2 significantly followed a negativelinear correlation pattern. No such relationexisted between the foregoing indices and PaCO_2 and PH. The author therefore considerlowered PaO_2 as a cause of abnormal hemorheology in silicosis. This study also showedη_p might be related to immunoglobulin level inblood. To elevate PaO_2 in time will be helpful for improving hemorheological condition ofpatients with silicosis.