逼尿肌漏尿点压在神经原性排尿功能障碍上尿路损害评估中的意义

Clinical significance of detrusor leak point pressure study in evaluating damage of the upper urinary tract secondary to neurogenic voiding dysfunction

目的 探讨逼尿肌漏尿点压检测神经原性排尿功能障碍患者上尿路损害功能评估中的诊断价值。 方法 38例神经原性排尿功能障碍患者行尿动力学检查 ,重点进行逼尿肌漏尿点压测定。 结果 以逼尿肌漏尿点压 4 .0kPa(1kPa=10 .2 0cmH2 O)为界将 38例患者分为高压 (n =2 6 )及低压 (n =12 )两组 ,高压组膀胱容量为 (42 2 .95± 183.2 7)ml,低压组为 (46 4 .83± 10 6 .4 3)ml,高压组逼尿肌顺应性较低压组低 ,逼尿肌尿道括约肌协同失调 (DSD)增高。B超、IVU、血尿素氮及血肌酐检查等临床指标检测显示逼尿肌漏尿点压高者上尿路损害机会较低压组显著增高。 结论 逼尿肌漏尿点压测定对神经原性排尿功能障碍患者上尿路损害状态的评估有较大价值。

Objective To evaluate clinical significance of detrusor leak point pressure (DLPP) in the damage of the upper urinary tract secondary to neurogenic voiding dysfunction. Methods 38 cases of voiding dysfunction received the urodynamic test,especially detecting of detrusor leak point pressure. Results 38 cases were divided into 2 groups by DLPP of 4.0 kPa,26 in high DLPP group and 12 in low DLPP group.The bladder capacity of the high pressure group is (422.95±183.27)ml,significantly less than the low pressure group (464.83±106.43)ml,and its compliance is lower as well as with DSD.Clinical results of B ultrasound,IVU,BUN,Cr show that the high pressure group has more serious than that in the low pressure group. Conclusions DLPP is valuable in evaluating the damage of upper urinary tract secondary to neurogenic voiding dysfunction.